The medical device may only be used by experienced personnel and only under certain conditions.
Use the PRP with particular caution in the following cases:
- acute or chronic infections at the surgical site;
- uncontrolled metabolic diseases such as diabetes, osteomalacia, thyroid dysfunction, severe kidney or liver disease;
- Long-term therapy with cortisone;
- Autoimmune diseases;
- Radiotherapy.
Patients with congenital or acquired functional platelet defects may release fewer growth factors.
In thrombocytopenia, it is very difficult to obtain a platelet-rich concentrate for clinical use. The platelet gel is reabsorbed within a few days. No toxicity phenomenon has been described in tissues treated with gel.
Normal monitoring procedures or prophylaxis against infectious complications should be used. Platelet-derived growth factors induce cell proliferation.
The use of platelet gel is contraindicated in suspected malignant degenerative lesions. To ensure tissue regeneration, the PRP must only be introduced into vital tissue and in direct contact with the tissue (if necessary, by applying microtints to the surface of the tissue).